DMC/DSMB Management Services 

Everest provides independent, end-to-end DMC/DSMB management—combining expert biostatistics, seamless committee administration and project management, and secure technology to ensure compliant, efficient, and trustworthy clinical trial oversight.

Frame 38

Your Partner for Independent
Data Monitoring

Since 2004, Everest has been a trusted partner in delivering comprehensive independent Data Monitoring Committee (DMC) and Data and Safety Monitoring Board (DSMB) services for clinical trials across a broad range of therapeutic areas. Our dedicated and agile teams—spanning biostatistics and programming, DMC/DSMB administration, and project management—bring deep expertise and a coordinated, independent approach to ensure rigorous, efficient, and compliant safety and study oversight throughout the clinical development process.

What We Offer

DMC Project Management & Administration

  • Act as primary liaison between sponsors and DMC
  • Identify DMC members and manage contracting and honoraria payments
  • Charter development and finalization
  • Scheduling, facilitating, and documenting DMC meetings

Biostatistical & Programming Expertise 

  • DMC and Interim SAPs with tailored report shells
  • Programming and validation of DMC data reports
  • Executive Summary creation and presentation (open/closed sessions)
  • Ad hoc analyses and SAE coordination
  • Periodic unblinded randomization code audits (as needed)

In-House Technology: Everest DMC Web Portal 

Our DMC projects are powered by our proprietary 21 CFR Part 11 compliant DMC Web Portal—ensuring secure, auditable, and user-friendly access to DMC documents.

Portal Highlights:

  • Role-based access for all stakeholders
  • Single-login credentialing for multi-project access
  • Document tracking with complete audit trails
  • A secure infrastructure providing confidence that your trial oversight processes are safe, efficient, and fully documented

Why Choose Everest for
Your DMC/DSMB Management? 

Our DMC services are designed for transparency, scientific rigor, and seamless coordination. Here’s how we do it:

Full-service Support

From identifying and engaging DMC members to charter development, statistical reporting, and meeting management and documentation, we handle all aspects of DMC management. 

Members of a DMC committee.